Not sure if this helps but my desk top piggy backs off the polycom ph and I connected the headset to the computer and make the calls through Skype. The wireless bit is a USB port.
Although this headset can be used for just listening to music, it was designed for interoffice communication apps such as Skype. The wireless range allows the user to move freely while communicating and not get caught up with the cord.
if you are using a wired headset that is connected to the USB port now Then i would say yes it should work because the h600 has a wirless connection that is paired automatically when you enter the wireless adapter into the usb port. hope this helps ..