You may try plugging it back into your computer.

Yes, but the button assignments may need to be changed or added manually. The remote software assigned my TV's directional controls to the remote's directional controls instead of the Channelmaster's directional controls. Also, there was no button assignment to access recorded programs.

The Logitec website has a tool on it where you can check to see if this remote can control your specific device (s) in question.

Almost certainly compatible, but you can easily check by going to Logitech support and the My Harmony device compatibility checker... https://support.myharmony.com/en-us/compatibility