Former United Nations employee Gerry Lane (Brad Pitt) is called upon to help stop the chaotic pandemic that has gripped populations around the world. Lane fights to keep his family safe, while searching for an answer to the outbreak before it destroys all of civilization.

2029 a female government cyber agent and the Internal Bureau of Investigations are hot on the trail of the Puppet Master - a computer virus capable of invading cybernetic brains and altering it's victim's memory. Created by the Ministry of Foreign Affairs and codenamed Project 2501, this 'hacker' is actually a prototype virtual agent which has now defied it's makers by seeking asylum within a new host body outside of the electronic net. Now the two agencies must maneuver against each another in a violent, high-tech race to capture the omnipresent entity. GHOST IN THE SHELL took the world by storm exhibiting a new dimension of anime with unprecedented and mesmerizing cinematic expression. Seamlessly merging traditional cel animation with the latest computer graphic imagery, this stunning sci-fi spectacle broke through the boundaries of mainstream animation with detailed artistic expression and a uniquely intelligent story line. The film has gone on to inspire a generation of filmmakers and has become the most revered anime feature of all time. Veteran anime writer/director/producer Mamoru Oshii, working in conjunction with the animators at Production I.G. (BLOOD THE LAST VAMPIRE, KAIDOHMARU, KILL BILL) brought to life Masamune Shirow's vision. This excellent cyberpunk thriller was co-produced by Manga Entertainment and enjoyed both critical and popular success at the U.S. box office and was the first Japanese animated film to reach No. 1 on the Billboard Top Video Sales Chart.