One of the biggest box office hits of all time delivers the ultimate encounter when mysterious and powerful aliens launch an all-out invasion against the human race. The spectacle begins when massic spaceships appear in Earth's skies. But wonder turns to terror as the ships biast destructive beams of fire down on cities all over the planet. Now the world's only hope lies with a determined band of survivors, uniting for one last strike against the invaders - before it's the end of all mankind.

Ten years after the events of Monsters, the 'Infected Zones' have now spread worldwide, and an American platoon is thrust into battle with a new breed of aliens. These soldiers embark on a life-altering mission through the dark heart of monster territory in the deserts of the Middle East. By the time they reach their goal, they will have been forced to confront the fear that the true monsters on the planet may not be alien after all.