In the waning days of World War II, the Navy warship USS Indianapolis secretly delivered one of two atomic bombs that would eventually end the war. The Japanese attacked and sank the heavy cruiser. The USS Indianapolis' mission was so classified it was not reported missing, and no one knew the ship had been attacked until four days later. Of the 1,197 crewmembers, nearly 300 went down with the ship. Stranded in the shark-infested waters of the Philippine Sea, the remaining survivors of the USS Indianapolis endured hunger, thirst, heat, delirium, relentless shark attacks and the death of many shipmates. Five days later only 316 men survived and were eventually rescued.

In this third globe-trotting screen adventure of Dan Brown's indefatigable iconologist Prof. Robert Langdon (Tom Hanks)-and another partnering for the star and director Ron Howard-a demented entrepreneur (Ben Foster) has decided to combat global overpopulation by unleashing a killer virus, and Langdon must unravel the madman's skein of Dante-themed clues to in order to find the doomsday weapon. Potent thriller co-stars Felicity Jones, Sidse Babett Knudsen, Irrfan Khan, Omar Sy.