Despite having solid field training, CIA analyst Susan Cooper (Melissa McCarthy) has spent her entire career as a desk jockey, working hand-in-hand with dashing agent Bradley Fine (Jude Law). Using high-tech equipment and a hidden earpiece, Susan is the guardian angel who helps Bradley avoid danger. However, when Bradley is assassinated by Bulgarian arms dealer Rayna Boyanov (Rose Byrne), Susan wrangles her way into her first undercover assignment to help capture Boyanov and avenge Bradley.

The year is 1912, and the United States is emerging as a world power. As an expression of the American ideals, the floating city of Columbia is launched with great fanfare. However, the endeavor of hope soon turns to disaster as the city disappears into the clouds. Pinkerton agent-turned-private investigator Booker DeWitt is sent to the floating city in search of a woman named Elizabeth, who has been imprisoned there since childhood. Will you be able to find Elizabeth and escape the city that is literally falling out of the sky before the powers that be put an end to your mission?Assume the role of former Pinkerton agent Booker DeWitt and set out to the floating city of Columbia to rescue an imprisoned woman in BioShock Infinite. Immerse yourself in the BioShock universe with DeWitt's identity, known past and a voice, which opens up new storytelling possibilities. Track down Elizabeth, a young woman who has been held captive in the city since childhood, and develop a relationship with her on your journey. Her vast array of abilities can aid you in combat and set up opportunities to combine with your powers in effective ways. Traverse the floating city along the intricate web of Sky-Lines that connect the floating city block islands, and engage in thrilling, high-speed battles. Encounter and interact with the citizens of Columbia to uncover their unpredictable motives and test their loyalty ~ or enmity.