These Drives will work regular desktop...However..They are not meant for performance...They only Spin at 5400RPM...and Have a 64mb Cache...
Also..Westerm Digital has replaced the Green Drives with Blue Drives.
Black and Certain Blue Drives spin at 7200RPM and have a 128mb cache.
Would only recommend REDs for Nas Boxes or Server Systems like freenas or unraid.
Hope that Helps