The first season of Hannibal follows FBI Agent Will Graham's (Hugh Dancy) as he becomes increasingly immersed in his efforts to find a brutal serial killer. When Special Agent Jack Crawford (Laurence Fishburne) pairs him with a highly skilled psychiatrist - who, unbeknownst to them, is the perpetrator himself, notorious serial killer Hannibal Lecter (Mads Mikkelsen) - Will questions his own sanity as his cannibalistic partner subjects him to a series of mind games.

Former United Nations employee Gerry Lane (Brad Pitt) is called upon to help stop the chaotic pandemic that has gripped populations around the world. Lane fights to keep his family safe, while searching for an answer to the outbreak before it destroys all of civilization.