Yes, there are two mics on both earbuds. This helps with the noise canceling feature. However, for Mono mode, you can only use the right earbud. That bud has the button that will let you take calls, put them on hold and switch between two calls. You would have to adjust volume with your phone. Since it is BT 5.0 you can also have it paired to two phones simultaneously. As far as losing one, these stay in the ear very well and have a recharging case to keep them in when not in use. The Jabra app also has "Find My Jabra" feature that gives a very precise location of where your earbud was last connected to your phone, as well as being able to turn the bud on remotely and have it emit as sound to help you locate it. I hope that this helps you in your decision.