Hello
I believe you can control two different tv's in the same room with this remote. If your tv's are used for different functions (watch cable tv, play games, etc.) then all you have to do is set the remote up with the function that you use it for. If this is not the case then you can still control two different tv's by choosing which tv you want to use in the remote "device" function and then choose the particular tv you want to control.
I hope this information has been helpful.