Janet,
Yes, there should be no issue using this mouse (or any) with his new MacBook Pro.
I use the same one with my MacBook pro.
If you have any issues check your settings under preferences or go to logitechs website and download any driver software needed.
Both of these solutions, if needed, are very quick and should take less than 1-2 minutes to complete.
Your husband is a lucky guy! Good gift selection!