There's no reason why it should'nt, However, if you are using a gaming motherboard, and are gaming, I would suggest investing in a Solid state drive for your OPS, and use a drive like this as storage for games music etc, and look into using ramdisk, for extra Speed for gaming, if you have enough RAM in your pc, as the game loads from storage onto your ram amd operated from the ram. Hope this helps.
SanDisk - SSD Plus 240GB Internal Serial ATA Solid State Drive
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