I seem to remember doing an internet search when I was going to purchase it and viewing the schematics for hook up of the CD player's back board. It may have been an online Onkyo manual for that specific model. You would probably want to do the same for your Bose product. I certainly would think it has the capability to be compatible to your Bose, but you'll just want to review that information and be certain the proper connection wiring is available to you, prior to purchasing. You could always contact Onkyo customer support by phone and ask them your question (have brand and model number specifics ready before you call). This recommendation comes with the "I'm just a normal consumer disclaimer-LOL"! Good luck your decision.