Hi Karl, Printed colors can never exactly match the colors on your computer monitor because printers and monitors use different color systems: monitors use RGB (red, green, and blue) and printers typically use CMYK (cyan, magenta, yellow, and black). Check the color matching and color management capabilities of your computer, display adapter, and the software you are using to see if they are affecting the palette of colors you see on your screen. Here are a few things you can try adjusting in the scanner settings. Change the Image Type setting and experiment with different combinations of the next settings, Adjust the Tone Correction setting, Adjust the Auto Exposure setting, Click Customize, then select the Color tab and adjust the Display Gamma setting to match your output device (monitor or printer), Select JPEG (*.jpg) or TIFF (*.tif) as the Type setting on the File Save Settings window. Regards, Mark - The Epson Team.