Thank you for the question. Yes, the Wacom Intuos tablet does work with a Lenovo Think Pad. As there are several different models of Thinkpads, please note that those with AMD Chips are not supported with the Wacom Drivers. Also, Chrome OS is supported with these OS requirements:Chrome OS 87 and later, and Kernel version 4 and later(including 4.4, 4.14 and 4.19. Regards