"Will this monitor fit in a 22" in space". No, not even close. The Viewsonic website Specifications for this monitor will provide a really good graphic with Width, Height, and Diagonal measurements.
"can it be adjusted down on the stand to that height from the full height of 25"?
If I understand your question, No. If you lower the monitor all the way down on the stand, you will have approximately 4 inches or 10 centimeters of clearance from the bottom edge of the monitor to your desktop.
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