Yes. I use it on a MacBook all the time. Works fine. When you first hook it up, system preference may ask you to set it up as a "wireless keyboard." Just click the advance button when the Mac asks you to click a key to set it up, and from that point on, you're all set.
The laser does not show up well on screens with a backlight (e.g. a TV). It does work well with screens that are projected on. I've tried it on both and have had much better success with a projection on a screen.
No it will not be visible on electronic tv's. I thought That it was broken when it didn't show up on the tv At first then I shined it in the wall and it was there. So no it will not show up interactive tv's.
Hi, the R400 Presenter Remote will not work with the Unifying Receiver. It uses it's on proprietary receiver. If you've misplaced your original one, here is the link to order a replacement: https://support.logi.com/hc/en-us/articles/360025400733--Spare-Parts-Wireless-Presenter-R400. Hope that helps!