That will depend on the compatibility and requirements of the keyboard and mouse you want to use. We recommend you check with the manufacturer of the keyboard and mouse at their web site web site for their compatibility with Windows 10 Home 64-bit operating system and the minimum/recommended hardware requirements (Is a Graphics card required, the processor speed and the minimum required system RAM and the minimum available hard drive space) to run their hardware, then compare those requirements to this system's configuration.

There is a 30-day trial of Microsoft Office 365 included as part of the Windows 10 operating system. In order to keep the program active after the trial period, you will need to purchase a product key. You will not need to download any additional software. Windows 10 S-Mode will update to the current version at the initial activation of Windows 10 S-Mode.

Yes, you can do this within Windows 10. Here is a link to instructions for doing this: https://support.microsoft.com/en-us/help/4092694/windows-10-file-sharing-over-a-network

That really will depend on the requirements and compatibility of the software you will be running. We recommend you check with the software publisher's web site for their compatibility with Windows 10 S-Mode 64-bit operating system (Windows 10 S-Mode provides added security by only allowing APPs available ( and therefore certified by Microsoft) at the Microsoft Store. If you don't need the added security or you need to install APPs not available at the Microsoft Store, you can switch to standard Windows 10 Home 64-bit Operating System, at no additional cost.) and the minimum/recommended hardware requirements (Is a Graphics card required, the processor speed and the minimum required system RAM and the minimum available hard drive space) to run their program, then compare those requirements to this system's configuration.