Yes, model number 81F500NSUS ships with a IPS LCD w/LED Backlight (Anti-glare) screen.

No, model number 90HV0005US does not ship with Intel Optane Memory. The Six-Core/Twelve Thread Intel Core i7-8700 does have Turbo Boost. The base speed of the processor is 3.2GHz and the Turbo Boost Speed is up to 4.6GHz.

Model number 81MV0001US does not have a CD/DVD drive built in. Yes this system is easy to initially setup. Just follow the audio instructions provided by Microsoft Cortana when you boot up the computer for the first time, or follow the onscreen instructions to activate Windows 10 for the first time. The heart of the Lenovo IdeaPad S145-15 laptop is the Windows 10 operating system. With regard to learning your way around Windows 10, you may want to try YouTube.com (just type that address in your browser address window). There are hundreds for free instructional videos there about Windows 10. Just type Windows 10 Introduction in to the YouTube search window. You can watch free videos there that will show you the basics all the way up to tips and tricks videos and they're all free. Finally, The lenovo S145-15 is an entry level, light use system with its Intel Pentium processor. It is not meant for multi-tasking or demanding programs. It is good for Microsoft Office and light internet browsing. If this describes your computing needs, the IdeaPad S145-15 would be a good choice. For 2018, Lenovo retained its place for a second year as the best laptop vendor:
https://www.laptopmag.com/articles/laptop-brand-ratings

The Lenovo IdeaPad 130-15 laptop is a mid-level, moderate use configuration, with its AMD A9-9425 processor. This Dual-Core processor has a base speed of 3.1GHz and a boost speed of up to 3.7GHz. This configuration has 4GB of DDR4-1866MHz RAM and a 128GB solid state hard drive. It is good for moderate Microsoft Office type programs. More advanced, resource hungry work with Microsoft Office programs that are extremely large and complicated, may be too much for this configuration.